Features on peer-reviewed research by scientists at The University of Tokyo.
Dr. Makoto Nakakido and colleagues designed humanized synthetic libraries of nanobodies, small antibody fragments first found in camels and llamas, that yield heat-stable binders to different targets.
Dr. Tomoki Kuwahara's team found that lysosomal stress drives immune cells of the macrophage lineage to release harmful α-synuclein through the LRRK2-Rab10 pathway.
Dr. Hayato Hirai and Professor Kunihiro Ohta found that when fission yeast run short of glucose, inactivation of the TOR complex triggers heterochromatin to form over ribosomal DNA.
