Recombinant Proteins Show Promise for Osteoporosis Treatment
Professor Mari Cleide Sogayar's team found that injecting the recombinant growth factors BMP-7 and PDGF-BB partially reversed bone loss in rats with surgically induced osteoporosis.
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Biomolecules
Features based on peer-reviewed papers published in Biomolecules.
Overcoming Drug Resistance in Macular Degeneration
Professor Yingbin Fu's team reviews why some macular degeneration patients stop responding to anti-VEGF drugs, and a combination approach targeting macrophages that showed promise in animals.
Melatonin: Beyond Sleep, Battling Infections
Dr. Georges Maestroni reviews evidence that melatonin can strengthen immune responses and curb inflammation in infections, while noting that clinical results so far are mixed.
Vigorous mitochondria are vital for favorable brain aging
Professor Stephen Bondy argues that failing mitochondria underlie brain aging by driving chronic inflammation, oxidative stress and disrupted nerve signalling, with changes beginning in mid-life.
Small Peptides Offer New Hope for Autoimmune Disease Treatment
Dr. Viktor Wixler's team found that small spleen peptides push dendritic cells toward a tolerance-promoting state by reshaping ATP signaling outside cells, and eased psoriatic skin inflammation in mice.