Decoding Yeast’s Gene Regulation Amidst Nutrient Scarcity
Dr. Hayato Hirai and Professor Kunihiro Ohta found that when fission yeast run short of glucose, inactivation of the TOR complex triggers heterochromatin to form over ribosomal DNA.
Field
Life Sciences
Molecular biology, genetics, microbiology, ecology and animal health.
Innovative Study Reveals neo-functionalization of TLR7 in pisciformes
Professor Jianguo Su's team found that fish TLR7, an immune sensor, has evolved to detect double-stranded as well as single-stranded viral genetic material, triggering antiviral and antibacterial defences.
Revolutionary Findings from Brazil on Breast Cancer Chemotherapy
In a Brazilian multicentre cohort, Professor Marcelo Antonini's team found that breast cancer patients whose tumours disappeared after pre-surgery chemotherapy had better long-term survival.
Aurora B Kinase A Key to Understanding Human Reproduction
Professor Juan Jimenez's team found in fission yeast that Aurora B kinase resets chromosome-microtubule attachments between the two meiotic divisions, ensuring sister chromatids separate correctly.
Revolutionizing Multiple Myeloma Treatment with New Therapy
Professor Julie O'Neal's team found that a long-acting IL-7 helped CAR-iNKT immune cells expand, persist and control multiple myeloma better in mice, with signs of lower inflammatory risk.
UNC-45A’s Role in Microtubule Curvature and Cancer Treatment
Professor Martina Bazzaro's team found that the protein UNC-45A prefers to bind curved microtubules and bends them even in the presence of Taxol, which normally straightens them.
Revolutionary Air Cleaning Tech Battles COVID-19 Spread
Professor Siddappa Byrareddy's team, working with Molekule, found that the company's air purifiers trapped and destroyed airborne SARS-CoV-2 in a test chamber and a testing facility.
Uncovering SARS-CoV-2’s Secrets with Wastewater Testing
Dr. Kristine Dye's team found that wastewater testing picked up shifts in coronavirus levels weeks before clinical tests and revealed mutations that may appear in future variants.
Unlocking the Secrets of Gene Regulation in Fruit Flies
Professor Bomyi Lim's team found that enhancer strength and long introns, but not promoters or exon length, change how fast RNA polymerase II moves along genes in fruit fly embryos.
Unraveling the Mysteries of Genetic Evolution: New Insights Revealed
Dr. Kimberly Gilbert's team found that self-fertilisation did not stop harmful mutations accumulating as the alpine plant Arabis alpina expanded its range.
Re-socialization is the key to chronic social isolation-induced anxiety and social memory impairment
Professor Daniela Rivera's team found that long-term social isolation raised anxiety-like behavior and impaired social memory in degus, and that later re-socialization reversed the behavioral changes.