Exploring AXL+ Siglec 6+ Dendritic Cells in HIV transmission and infection
Dr. Najla Nasr's team found that AXL+ SIGLEC-6+ dendritic cells gather in inflamed human genital tissues, capture HIV and pass it to CD4 T cells in two distinct phases.
Features on peer-reviewed research by scientists at Westmead Institute for Medical Research.
Dr. Najla Nasr's team found that AXL+ SIGLEC-6+ dendritic cells gather in inflamed human genital tissues, capture HIV and pass it to CD4 T cells in two distinct phases.
Professor Andrew Harman's review explains that dendritic cells, not only Langerhans cells, capture viruses in skin and mucosal linings, with implications for designing vaccines that work at these surfaces.