Clinical studies, public health, pharmacology and the biology of disease.
Dr. Ilya Tsimafeyeu's team found that an antibody blocking the FGFR1 receptor shrank lung tumours in animal models and strengthened the effect of existing immunotherapy drugs.
Dr. Venkata Buddharaju and David Shelton describe a reusable, adjustable silicone catheter for men that held without leaks in bench tests and that nurses in a small hospital evaluation preferred.
Dr. Akiyoshi Saitoh's team found that activating oxytocin cells in the mouse hypothalamus that project to the supramammillary nucleus strengthened the animals' memory for recognising objects.
Dr. Micah Ngatuvai's team found that executive pay at American non-profit hospitals rose steadily across all regions, with links to financial performance that were not straightforward.
James Repace documents nonsmokers in apartments across the United States and Canada whose homes were infiltrated by neighbours' smoke, confirmed by nicotine monitors, and who reported breathing problems and other symptoms.
Dr. Hong-Hong Zhu's team found that drinking alcohol was linked to a higher colorectal cancer risk in women in Quzhou, China, while men who drank showed no clear increase.
Dr. Matthew Ahmadi's team found that long daily sitting was linked to higher heart and circulatory disease risk, while long standing was linked to circulatory problems but not heart disease.
Dr. Fanny Chapelin's team used fluorine-based MRI to follow macrophages gathering in mouse breast and colon tumours after radiation, revealing different immune responses between the cancer types.
Professor Joe Hasei's team found that young people with rare cancers spoke more freely and found peer support when meeting as avatars in a virtual metaverse space.
Dr. Frank Duca's team found that, of several plant fibers tested in mice on a high-fat diet, only β-glucan curbed weight gain and improved blood sugar control.
Dr. Victor Sanchez-Merino's team found that in adults and children with suppressed HIV, broader neutralising antibody responses were linked to later treatment start and lower CD4/CD8 ratios.
Dr. Gabriel Solana-Lavalle's team developed an interpretable machine learning method that identifies Parkinson's disease from resting brain scans and highlights the brain regions most affected.
