Zooming In: New Tech Reveals Tumor Immune Tactics
Jane Siu-Fan Li and colleagues describe a step-by-step laboratory protocol for staining several immune markers at once in tumor tissue, letting researchers map how immune and cancer cells interact.
Featured journal
STAR Protocols
Features based on peer-reviewed papers published in STAR Protocols.
Gene expression in brain cells studied with high resolution
Dr. Xiaokuang Ma and colleagues describe a protocol for preparing fixed frozen mouse brain sections for Xenium spatial transcriptomics, mapping gene activity in individual cells with less tissue damage.
Tracking Azelaic Acid defense signal to Boost Plant Disease Resistance
Professor Jean Greenberg and Dr. Nicolás Cecchini describe methods that use isotope-labeled azelaic acid to trace how this defense signal moves through Arabidopsis plants and enters leaf tissue.
Cost-Effective Method Simplifies Gene Editing in Drosophila
Dr. Yu-Chieh David Chen's team describes a protocol that uses genetic crosses instead of microinjection to make gene-specific split-GAL4 lines in fruit flies, lowering cost and complexity.
Pivotal role of chicken lens cells in improving eye health
Dr. Jean Jiang's team describes a step-by-step protocol for altering connexin hemichannel function in chicken lens fiber cells with a retrovirus, then testing cell survival under oxidative stress.