Heart Anatomy Quirk Leads to False Tumor Alarm in Imaging
Dr. Busra Cangut's team describes a breast cancer patient whose PET/CT scan suggested a tumor clot in the heart that proved to be a normal ridge of heart tissue.
Field
Health & Medicine
Clinical studies, public health, pharmacology and the biology of disease.
New Precision Cancer Therapy Targets Hard-to-Treat Tumors
Dr. Brad St. Croix's team re-engineered an antibody-drug conjugate targeting CD276, widening its safety window so lower doses eliminated large solid tumours ahead of clinical trials.
Pioneering Skin Cancer Treatment Offers New Hope
Dr. Jung Hyun Lee's team found in laboratory models that pairing palbociclib with a HIF2α inhibitor promoted immune-triggering cell death, including ferroptosis, in Merkel cell carcinoma cells.
A Global Vaccine Alliance to Combat Emerging Infectious Diseases
Professor Weikuan Gu and colleagues propose InterVax, an international pool of pre-developed vaccine candidates intended to speed responses to future respiratory pandemics and widen fair access.
Brain’s immune system comes to the rescue and aids in repair
Dr. Jason Plemel's team found that microglia, the brain's immune cells, help start myelin repair by supporting the recruitment of progenitor cells, beyond simply clearing myelin debris.
What is the mechanism behind traumatic brain injury susceptibility? The relevance of mitochondrial and vascular dysfunction
Dr. Gerben van Hameren's team found that mitochondrial damage after traumatic brain injury in animals underlies abnormal blood vessel responses during spreading depolarisations linked to poorer outcomes.
Aging, Muscles, and Kidney Health: A New Study Explores Gender Differences
Professor Jeong-Ho Kim's team found that blood creatinine falls more with age in older men than older women because men lose more muscle, which can skew kidney function estimates.
The Silent Danger in Turkey Farms: A Bacterial Menace Revealed
Dr. Guillermo Tellez-Isaias's team found that Streptococcus gallolyticus, usually a harmless gut bacterium, caused rapid and fatal infections in young turkeys and may spread between birds.
Thailand’s Battle Against Rising Diabetes Trends
Patcharee Numsang's team interviewed people with type 2 diabetes in northeastern Thailand and found that self-care habits, misperceptions and cultural beliefs contributed to poorly controlled blood sugar.
Aquatic Life’s Sense of Smell at Risk from Nano Zinc
Dr. Aya Takesono's team found that low, non-lethal doses of zinc oxide nanoparticles inflamed smell tissues in young zebrafish and impaired their smell-driven behavior.
Exploring Long-COVID: How It Affects the Human Brain and Hormones
Dr. Vincent Prevot's team found that the COVID-19 virus can infect and kill brain cells that make the reproductive hormone GnRH, which may explain lasting low testosterone and cognitive problems in men.
New Study Sheds Light on Breast Cancer’s Genetic Drivers
Professor Wei Gu's team found that the long noncoding RNA MACC1-AS1 partners with the protein DDX5 to switch on MACC1, a gene linked to cancer spread, in breast cancer cells.