Breaking New Ground with AI in Intensive Patient Care
Dr. Andrew Kramer's team reports that showing ICU clinicians a machine-learning warning score, ViSIG, was linked to shorter ICU stays, less ventilation time and fewer readmissions.
Field
Health & Medicine
Clinical studies, public health, pharmacology and the biology of disease.
The Ripple Effect of COVID-19 on Women’s Health in Ontario
Dr. Rui Fu and Dr. Antoine Eskander's team found that breast cancer screening in Ontario fell sharply when the pandemic began and had not recovered to earlier levels.
The Impact of Red vs. Blue State Policies on COVID-19 Deaths
Dr. Dominik Güss's team found that US states with Republican and Democratic leadership differed in COVID-19 mitigation rules, vaccination rates and death rates during the pandemic.
The Hidden Risks of Treating ADHD and Depression in Recovery from Drug Addiction
Professor Michela Marinelli's team found that methylphenidate, alone or combined with fluoxetine, reignited cocaine-seeking behaviour in rats, raising concerns about relapse risk in former cocaine users.
The Unseen Risks of Treating Teen ADHD with Common Medications
Professor Panayotis Thanos's team found that adolescent rats given Ritalin together with the antidepressant fluoxetine later self-administered more cocaine than rats that had only water.
Health prep of Fruits and Veggies toward better kidney health
Professor Donald Wesson's trial found that African American adults with signs of kidney damage who received cooking instructions with fruits and vegetables showed larger drops in kidney damage markers.
The Hidden Dangers Behind Treating ADHD and Depression Together
Professor Heinz Steiner's team found that adding the antidepressant fluoxetine to methylphenidate amplified the stimulant's effects in rats, and some of those rats later took more cocaine.
The Future of Fighting Cancer Lies in Our Genes
Dr. Anthony Serritella's team found that variants in the immune gene FcγRIIIA may influence how patients with advanced gastroesophageal cancer respond to antibody drugs, with a trend towards longer survival.
Saliva-Based Diagnostics: Changing the Face of Respiratory Healthcare
A review led by Dr. Anne Wyllie finds that saliva detects many respiratory pathogens about as well as swabs and carries immune markers useful for surveillance, though collection needs standardizing.
When Sunshine and Genes Collide: A New Look at Vitamin D
Dr. Narmada Ashok and Dr. Radha Saraswathy compared South Indian children with and without asthma or allergic rhinitis and linked variants in vitamin D pathway genes to these conditions.
Simplifying Virus Detection for Quicker Pandemic Response
Dr. Asif Awaludin and Dr. Hesti Wiraswati refined heat-based and magnetic-bead methods for extracting viral genetic material, aiming to speed testing in laboratories with limited resources.
Breaking Barriers in Healthcare with Bioink-Based Tissue Regeneration
Dr. Xiongbiao Chen and colleagues review the physical, flow and biological properties bioinks need for extrusion bioprinting of tissues and laboratory tissue models.