Molecular biology, genetics, microbiology, ecology and animal health.
Dr. Piotr Golec's team engineered bacteria-killing viruses to carry silver nanoparticles and found in lab tests that they broke down bacterial biofilms better than either component alone.
Professor Jing Chen's team found that adding a phosphate at a single site on the protein Huluwa switches on signaling that sets up the body axis in fish and frog embryos.
Dr. Xiaokuang Ma and colleagues describe a protocol for preparing fixed frozen mouse brain sections for Xenium spatial transcriptomics, mapping gene activity in individual cells with less tissue damage.
Dr. Amanda Murti's team found that carefully matched African green monkeys in research facilities mostly did well in same-sex pairs and trios, with females adapting best and male trios hardest.
Dr. Esther Natalie Oliva's team found that older patients with acute myeloid leukemia given azacitidine after remission stayed in remission longer, and linked certain gene mutations to higher relapse risk.
Professor Baoguo Li's team recorded a wild golden snub-nosed monkey mother adopting and nursing an unrelated infant fathered by her group's dominant male, possibly to protect her own baby.
Dr. Cong Ji and Dr. Junbin Shao developed Epi-Clock, which tracks genetic changes in coronavirus data and, in tests on past COVID-19 outbreaks, picked up early signs before cases surged.
Dr. Ergun Akturk and Professor Tom Coenye found that giving bacteriophages before antibiotics cleared mixed Pseudomonas and Staphylococcus infections better in a lab-grown lung tissue model than other orders.
Dr. Caghan Kizil and Dr. Konstantinos Ampatzis found that the zebrafish heart's own nervous system holds diverse nerve cell types, some firing rhythmically like pacemakers, suggesting it helps regulate heartbeat.
Dr. Makoto Nakakido and colleagues designed humanized synthetic libraries of nanobodies, small antibody fragments first found in camels and llamas, that yield heat-stable binders to different targets.
Dr. Carolina Parada's team sequenced intracranial epidermoid cysts and found recurrent NOTCH2 and USP8 mutations and immune-related changes, pointing to existing drugs that might be tested against them.
Professor Geert Schmid-Schönbein's team found that in older rats, digestive enzymes leaked from a weakened gut into organs and damaged tissue, and an enzyme blocker reduced this.
